Figure 1.

Properties of the G. lamblia cpn60 gene and mRNA transcript. Upstream and downstream regions of the cpn60 gene are shown and numbered relative to the first base of the start codon (+1). The transcriptional start sites are shown in bold under vertical lines and rightward-pointing arrow (→). Two possible transcriptional signals are identified: an AT-rich transcription initiation signal (single underline), and an upstream promoter element (double underline) similar to the CAATTT signal reported for other G. lamblia genes (33). Possible sites of polyadenylation (↓), a putative polyadenylation signal (boxed), and the stop codon (∗) are also indicated.