Abstract
Pharmacokinetic parameters of cefaclor were studied in eight patients after an oral dose of 250 mg. Serum samples were obtained before and on 19 occasions after oral administration. Cefaclor serum concentrations were determined by a new high-performance liquid chromatographic technique.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bach V. T., Khurana M. M., Thadepalli H. In vitro activity of cefaclor against aerobic and anaerobic bacteria. Antimicrob Agents Chemother. 1978 Feb;13(2):210–213. doi: 10.1128/aac.13.2.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Berman S. J., Boughton W. H., Sugihara J. G., Wong E. G., Sato M. M., Siemsen A. W. Pharmacokinetics of cefaclor in patients with end stage renal disease and during hemodialysis. Antimicrob Agents Chemother. 1978 Sep;14(3):281–283. doi: 10.1128/aac.14.3.281. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bill N. J., Washington J. A., 2nd Comparison of in vitro activity of cephalexin, cephradine, and cefaclor. Antimicrob Agents Chemother. 1977 Mar;11(3):470–474. doi: 10.1128/aac.11.3.470. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bloch R., Szwed J. J., Sloan R. S., Luft F. C. Pharmacokinetics of cefaclor in normal subjects and patients with chronic renal failure. Antimicrob Agents Chemother. 1977 Dec;12(6):730–732. doi: 10.1128/aac.12.6.730. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cockcroft D. W., Gault M. H. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31–41. doi: 10.1159/000180580. [DOI] [PubMed] [Google Scholar]
- Foglesong M. A., Lamb J. W., Dietz J. V. Stability and blood level determinations of cefaclor, a new oral cephalosporin antibiotic. Antimicrob Agents Chemother. 1978 Jan;13(1):49–52. doi: 10.1128/aac.13.1.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Korzeniowski O. M., Scheld W. M., Sande M. A. Comparative pharmacology of cefaclor and cephalexin. Antimicrob Agents Chemother. 1977 Aug;12(2):157–162. doi: 10.1128/aac.12.2.157. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rotschafer J., Crossley K., Zaske D., Viste R. Comparative study of cefaclor and amoxicillin in treatment of urinary tract infection. Urology. 1979 Sep;14(3):233–236. doi: 10.1016/0090-4295(79)90489-8. [DOI] [PubMed] [Google Scholar]
- Sanders C. In vitro studies with cefaclor, a new oral cephalosporin. Antimicrob Agents Chemother. 1977 Oct;12(4):490–497. doi: 10.1128/aac.12.4.490. [DOI] [PMC free article] [PubMed] [Google Scholar]