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. 2000 Apr 11;97(8):4174–4179. doi: 10.1073/pnas.97.8.4174

Figure 6.

Figure 6

A loss of heterozygosity study of tumors from p53R172HΔg/+ mice. SSCP analysis was performed on tumor samples obtained by using laser capture technology. (a) LOH analysis of DNA from osteosarcomas from mice numbered 395 and 565 using A3 and A4 primers (see Materials and Methods). 565N indicates DNA isolated from normal tissue adjacent to tumor of mouse 565. (b) LOH analysis of DNA from a carcinoma from mouse 3124 using primers A3 and Mie5R (see Materials and Methods). Tail DNA from wild type (+/+), homozygous (Δg/Δg), and heterozygous (Δg/+) mice were used as controls to distinguish the two alleles.