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. 2000 Apr 4;97(8):4192–4197. doi: 10.1073/pnas.050417697

Figure 2.

Figure 2

IL-2/Ig protein and IL-2/Ig plasmid administration lead to significant CD25 expression on CD3+ PBL of the vaccinated monkeys. The monkeys were bled at week 0, week 1, week 2, and every 2 weeks thereafter. Gated CD3+ lymphocytes from whole blood were examined for staining with an anti-CD25 mAb by flow cytometry. The monkeys that received IL-2/Ig protein demonstrated a striking rise and rapid fall of CD25 expression. The monkeys that received IL-2/Ig plasmid showed a less dramatic but more sustained increase in CD25 expression. Means and SE for each group are shown.