TABLE 1.
Measurement | Wild-type (n = 8) | Transgenic (n = 7) |
---|---|---|
Geometry | ||
Weight (g) | 32.2 ± 4.3 | 35.1 ± 3.4 |
Vertebral height (mm) | 3.4 ± 0.1 | 3.4 ± 0.1 |
Vertebral depth (mm) | 1.3 ± 0.1 | 1.4 ± 0.1 |
Vertebral width (mm) | 2.1 ± 0.4 | 2.3 ± 0.2 |
BMD (mg/mm2) | 61.1 ± 3.1 | 62.4 ± 4.6 |
Histomorphometry | ||
Bone area (%) | 13.1 ± 3.3 | 13.4 ± 1.8 |
Trabecular width (μm) | 35.2 ± 4.6 | 35.6 ± 2.8 |
Trabecular spacing (μm) | 241.9 ± 41.2 | 233.5 ± 29.0 |
Trabecular number (/mm) | 3.7 ± 0.5 | 3.8 ± 0.4 |
Wall width (μm) | 7.3 ± 0.6 | 6.8 ± 1.2 |
Osteoid area (%) | 1.6 ± 0.7 | 1.9 ± 0.8 |
Osteoid width (μm) | 2.4 ± 0.2 | 2.5 ± 0.2 |
Osteoblast number (mm) | 6.6 ± 1.9 | 7.2 ± 1.8 |
Osteoclast number (mm) | 1.9 ± 0.3 | 1.7 ± 0.7 |
Values are given as mean ± SD of measurements.