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. 2006 Jun 8;575(Pt 1):145–159. doi: 10.1113/jphysiol.2006.112730

Figure 3. Pretreatment with a GABAB receptor antagonist enhanced distal GABAA IPSCs from ILS mice but not from ISS mice.

Figure 3

Ethanol (80 mm) did not significantly affect GABAA IPSCs for either proximal or distal GABAA IPSCs from ISS mice, whereas ethanol (80 mm) alone enhanced proximal, but not distal GABAA IPSCs from ILS mice. Pretreatment with CGP-52432 did not significantly alter the effect of ethanol on these responses from ISS mice. However in ILS mice, although CGP-52432 pretreatment did not further enhance the effect of ethanol (80 mm) on proximal responses, it significantly enhanced distal GABAA IPSCs. Number of cells for these experiments ranged from 6 to 12 for each individual determination. *P < 0.05; **P < 0.01.