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. 2006 Jun 8;575(Pt 1):145–159. doi: 10.1113/jphysiol.2006.112730

Figure 5. Acute ethanol inhibits NMDA EPSCs from ISS and ILS mice in a concentration-dependent manner.

Figure 5

A, superfusion of ethanol (40, 80 or 120 mm) for 10 min decreased evoked NMDA EPSC amplitudes in both representative ISS and ILS mice. B, mean percentage inhibition of NMDA EPSC amplitudes shows differences in ethanol responses: ILS EPSCs are more sensitive to ethanol than those from ISS mice. Number of neurons for each ethanol concentration: 40 mm, n = 5; 80 mm, n = 6; 120 mm, n = 7, in ISS mice; and 40 mm, n = 5; 80 mm, n = 7; 120 mm, n = 6 in ILS mice. Scale for A: ISS, 50 ms, 20 pA; ILS, 50 ms, 15 pA.