Figure 2. Electric field stimulation (EFS)-evoked contractions of guinea-pig tracheal strips in vitro before and after pretreatment with vehicle (DMSO; A) 50 μm FM2-10 (B) or 5 μm FM1-43 (C).

Data represent the means ±s.e.m. of n = 3–4 experiments and are expressed as a percentage of the maximum attainable contraction evoked by 300 mm BaCl₂. See Table 1 for estimated IC₅₀ values. *P < 0.05, significantly different compared to before the treatment.