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. 2006 May 25;575(Pt 1):83–100. doi: 10.1113/jphysiol.2006.110486

Figure 3. Expression of HCN2 (top row) and HCN4 (bottom row) mRNA in selected thalamic nuclei does not differ in GAERS and NE controls.

Figure 3

A, representative coronal brain sections at the level of the thalamus that have been subjected to quantitative in situ hybridization for the HCN2 channel isoform. The preferential expression of this isoform in thalamus is apparent. B and C, quantitative analysis of mRNA expression levels of HCN2 channels comparing GAERS to NE rats. The strains are not distinguishable in the expression of this isoform. D, representative sections of GAERS and NE rat brain for HCN4 mRNA expression. Note the relatively lower expression of this isoform in the Rtn, and the typical signal of HCN4 in the habenula, supporting the specificity of the probes. E and F, quantitative analyses of HCN4 mRNA expression indicate the absence of significant differences in GAERS versus NE. Hb = habenula.