Figure 5. Mature GAERS TC cells generate unaltered afterdepolarizations (ADPs).

A and D, representative ADPs (arrow) found in TC cells from mature NE rats (A) and GAERS (D). The asterisk (*) denotes a fast ADP that is not mediated by I_h. The current injection protocols used to elicit the ADPs in A and D are shown below the traces. B and E, cells showing spontaneous clock-like δ-oscillations in a TC cell of a NE animal (B) and a GAERS (E). Note the attenuation of these oscillations during the ADP and their gradual reappearance. C, the slow ADP, shown here for a NE control (slow ADP-ctrl), is blocked in the presence of 3 mm Cs⁺ in the superfusing solution (slow ADP – Cs⁺ 3 mm). F, pooled values of ADP amplitudes for all experiments (n = 24 for both strains). Filled circles denote results of individual experiments, and are sometimes superimposed on each other. Average values (open circles) were not significantly different (NS).