Figure 3.

Effect of 1F7 or TEPC 183 injections on the neutralization response against HIV-1 IIIB in four macaques. Data are shown for the four monkeys as in Fig. 2. Macaques 441-91, 149-93, and 337-91 displayed in A, B, and C were inoculated with mAb 1F7; macaque 42-93 was inoculated with isotype control mAb TEPC 183 (D). Selected time points (prebleed and days after the first mAb inoculation) are represented as serial serum dilutions (x axis) versus the reduction in the virus surviving fraction (V_n/V₀) on the y axis. The vertical bars indicate the standard error of the predicted means from the fitted regression curve (17).