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XCPE1 is an activator-dependent core promoter. (A) The sequences of the wild-type X gene core promoter 1 and the mutant promoters containing no NRF1-binding site (XCPE1 alone) or a tandem repeat of NRF1, NF1, or Sp1-binding sites are shown. (B) In vitro transcription from templates containing NRF1, NF1, or Sp1-binding sites upstream of XCPE1.
