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. 2007 Jan 6;27(5):1881–1888. doi: 10.1128/MCB.01122-06

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FIG. 3. — Key parameters related to the DNL pathway in the liver. (A) DNL and (B) TG levels in the livers obtained from Acc1^+/+ WT (+/+:WT; black column; n = 10), Acc1^{lox(ex46)/lox(ex46)} WT (lox/lox:WT; gray column; n = 9), and Acc1^{lox(ex46)/lox(ex46)} Tg^Fabpl-cre (lox/lox:cre; open column; n = 10) mice. (C) Relative Acc1 (black column) and Acc2 (open column) and (D) Mcd mRNA levels in the livers obtained from +/+:WT (n = 10), lox/lox:WT (n = 9), and lox/lox:cre (n = 10) mice. ***, P < 0.001 compared with +/+:WT (for Acc1); #, P < 0.05; ###, P < 0.001 compared with +/+:WT (for Acc2). (E) Malonyl-CoA level in the livers obtained from +/+:WT (black column; n = 5) and lox/lox:cre (open column; n = 6) mice fed with a normal chow diet or fasted for 16 h. ##, P < 0.01 for fed versus fasted groups within the same genotype. (F) FAO in the livers obtained from +/+:WT (black column; n = 10), lox/lox:WT (gray column; n = 9), and lox/lox:cre (open column; n = 11) mice. Each column represents average results ± standard errors.