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Inhibition of rhURO-D by denatured human cytosolic extracts. Biopsy samples ranging in weight from 8 to 22 mg were processed as described (see Materials and Methods) and assayed for inhibition of rhURO-D activity. Samples H1–H4 were obtained from untreated patients with hemochromatosis. Samples P1–P4 were obtained from untreated patients with PCT. Sample P2 was from a patient with F-PCT. All other porphyric samples were from patients with S-PCT.
