Table 3.

Childhood urinary symptoms as risk factors for adult lower urinary tract symptoms

	Adult Urinary Symptoms
	Daytime Void Frequency†	Nocturia‡	Urgency§	Stress UI Weekly or More	Urge UI Weekly or More	More Than 1 UTI in last 12 Mos
Childhood Urinary Symptoms*
Daytime frequency:
Adjusted OR∥	1.30	1.36	1.88¶	0.97	0.76	1.08
95% CI	0.91–1.86	0.96–1.92	1.32–2.69	0.59–1.58	0.41–1.41	0.68–1.71
Nocturia:
Adjusted OR∥	1.63*	2.27¶	1.14	1.26	0.69	1.48
95% CI	1.05–2.54	1.47–3.5	0.71–1.83	0.66–2.41	0.19–1.44	0.85–2.57
Daytime UI:
Adjusted OR∥	0.82	0.50**	0.96	1.60	2.56**	0.87
95% CI	0.46–1.47	0.27–0.93	0.55–1.68	0.72–5.59	1.11–5.9	0.41–1.85
Nocturnal enuresis:
Adjusted OR∥	1.09	0.67	0.94	0.57	2.68††	0.65
95% CI	0.66–1.79	0.41–1.10	0.58–1.53	0.25–1.34	1.32–5.46	0.33–1.29
UTIs (1 more than yr):
Adjusted OR∥	1.19	1.59	1.47	2.00**	2.03	2.80¶
95% CI	0.70–2.05	0.95–2.66	0.86–2.52	1.00–3.90	0.93–4.46	1.60–4.90

^∥Odds ratios with 95% confidence intervals adjusted for age (10-year intervals), race, parity (0, C-section only, 1 vaginal delivery, 2+ vaginal delivery), body mass index at age 25 (less than 25/25–30/greater than 30) kg/m² hysterectomy (yes/no), current oral estrogen use, diabetes, chronic lung disease and prior stroke (yes/no).

^*Childhood urinary symptoms defined as present when participant recalled that the symptom was present sometimes or always between first grade and high school.

^†Daytime frequency defined as present when reported daytime voiding frequency was greater than 7 voids daily.

^‡Nocturia defined as present when reported nighttime voiding frequency was greater than 1 void nightly.

^§Strong urgency defined as present when participant reported presence of a strong urge or pressure to urinate without actually leaking, monthly, weekly or daily.

^¶p < 0.001.

^**p < 0.05.

^††p < 0.01.