Table 2.

Dendritic spine changes in the Tg2576 cortex

	n (spines)	Spine density (spines/μm)	Spine length (μm)	Mushroom (length, % total)	Thin (length, % total)	Stubby (length, % total)
Control	220	0.33 ± 0.12	1.25 ± 0.54	1.47 ± 0.60, 23.9 ± 9.7%	1.26 ± 0.49, 56.6 ± 15.8%	0.74 ± 0.21, 19.3 ± 13.5%
Tg2576 total	364	0.24 ± 0.08**	1.24 ± 0.64	1.51 ± 0.74, 26.3 ± 17.6%	1.25 ± 0.57, 56.9 ± 19.7%	0.69 ± 0.25, 21.8 ± 15.7%
Tg2576<15 μm from plaque	76	0.16 ± 0.07**	1.19 ± 0.58	1.33 ± 0.62, 24.0 ± 17.1%	1.16 ± 0.56, 55.0 ± 17.8%	0.65 ± 0.22, 25.3 ± 20.2%
Tg2576>15 μm from plaque	288	0.27 ± 0.07**	1.25 ± 0.66	1.58 ± 0.78 27.2 ± 18%	1.28 ± 0.57, 52.1 ± 20.6%	0.69 ± 0.25, 20.8 ± 13.6%

^**p<0.001 compared with control.