Table 3.
Gene | Locus/variant | Subjects/phenotypic trait | (a) Assoc. | References |
| ||||
PPAR-γ Gene | D3S1263 | PCOS | No | Urbanek et al. [35] |
| ||||
Pro12Ala | PCOS/reduced insulin resistance | Yes | Hara et al. [176] | |
PCOS/lower hirsutism scores, | Yes | Hahn et al. [177] | ||
increased insulin sensitivity | ||||
Reduced insulin resistance | (b) Yes | Tok et al. [178] | ||
PCOS | Yes | Korhoren et al. [179] | ||
PCOS | No | San Millán et al. [163] | ||
PCOS | No | Orio et al. [182] | ||
| ||||
PCOS/clinical and hormonal | Yes | Yilmaz et al. [181] | ||
characteristics | ||||
| ||||
CAC478CAT | PCOS/obesity, leptin levels | Yes | Orio et al. [182] | |
| ||||
PPAR-γ & | Pro12Ala & | PCOS | No | Wang et al. [183] |
PGC-1α | Gly482Ser |
(a)Assoc.: association. (b) No statistical significance.