Table 3.
Genes involved in energy homeostasis: PPAR-γ.
| Gene | Locus/variant | Subjects/phenotypic trait | (a) Assoc. | References |
|
| ||||
| PPAR-γ Gene | D3S1263 | PCOS | No | Urbanek et al. [35] |
|
| ||||
| Pro12Ala | PCOS/reduced insulin resistance | Yes | Hara et al. [176] | |
| PCOS/lower hirsutism scores, | Yes | Hahn et al. [177] | ||
| increased insulin sensitivity | ||||
| Reduced insulin resistance | (b) Yes | Tok et al. [178] | ||
| PCOS | Yes | Korhoren et al. [179] | ||
| PCOS | No | San Millán et al. [163] | ||
| PCOS | No | Orio et al. [182] | ||
|
| ||||
| PCOS/clinical and hormonal | Yes | Yilmaz et al. [181] | ||
| characteristics | ||||
|
| ||||
| CAC478CAT | PCOS/obesity, leptin levels | Yes | Orio et al. [182] | |
|
| ||||
| PPAR-γ & | Pro12Ala & | PCOS | No | Wang et al. [183] |
| PGC-1α | Gly482Ser | |||
(a)Assoc.: association. (b) No statistical significance.