Table 1.
Type 2 diabetic subjects (n = 11) | Control subjects (n = 8) | |
---|---|---|
Age (years) | 62 ± 2 | 58 ± 1 |
Height (cm) | 177 ± 3 | 179 ± 1 |
BMI (kg/m2) | 32 ± 2* | 28 ± 1 |
Time since diagnosis (years) | 5 ± 2 | – |
Fasting insulin (pmol/l) | 61 ± 9* | 34 ± 6 |
Fasting glucose (mmol/l) | 9.0 ± 0.5* | 5.4 ± 0.1 |
Complex I activity (nmol min−1 mg protein−1) | 50.8 ± 6.0 | 58.3 ± 4.7 |
Citrate synthase activity (pmol mg−1 s−1) | 1.6 ± 0.1 | 2.0 ± 0.2 |
mtDNA (copies/μg tissue) ×103 | 119 ± 7* | 147 ± 12 |
mtDNA/genomic DNA | 2,773 ± 252 | 3,030 ± 185 |
Data are means±SEM. *p < 0.05 vs control subjects