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. 2007 Feb 13;5(3):e43. doi: 10.1371/journal.pbio.0050043

Figure 8. Two In Vivo Cases of Combined Chromosomal Translocation and Reintegration of an Excised EC.

Figure 8

The insertion of a (Jδ1/Dδ2) ESJ (red, upper cases) into (A) a Jβ2.7/Vδ2 trans-TCR or (B) a Dβ1/Vδ2 trans-TCR CSJ target (black, lower cases) is depicted; alternatively, ESJ reintegration could have occurred first, and provided a trans-TCR structure and/or breakpoints prone to V(D)J-mediated translocation. Breakpoint junctions are boxed. Black bold upper case type: N nucleotides; heptamers and nonamers are underlined. PCR primers are indicated, and shown in italics in the sequence.