Table 3.
Brain tissue volumes from segmentation
Diagnosis | cGM | sGM | WM | sCSF | vCSF | WMSH |
---|---|---|---|---|---|---|
Control | 503 ± 28* | 18 ± 3 | 459 ± 31* | 267 ± 43 | 46 ± 14* | 5 ± 6* |
AD | 458 ± 40 | 17 ± 5 | 419 ± 37 | 319 ± 52 | 66 ± 22‡ | 8 ± 7† |
Percent change | −10 | −6 | −9 | 19 | 43 | 60 |
SIVD | 438 ± 42* | 15 ± 4 | 426 ± 36* | 286 ± 65 | 85 ± 24*‡ | 45 ± 39*† |
Percent change | −13 | −17 | −7 | 7 | 85 | 800 |
Data represented as mean ± SD in units of cm3. Percent change compared with cognitively normal subjects.
p < 0.01 subjects with SIVD vs cognitively normal subjects.
p < 0.01,
p < 0.05 subjects with SIVD vs subjects with AD.
cGM = cortical gray matter; sGM = subcortical gray matter; WM = white matter; sCSF = sulcal CSF; vCSF = ventricular CSF; WMSH = white matter signal hyperintensities; SIVD = subcortical ischemic vascular dementia.