TABLE 3.

Raw Data Summaries: NAA and mI Concentrations and Selected Metabolite Ratios of Parietal GM, Frontal GM, Parietal WM, and Frontal WM in AD (N = 14) and CN (N = 22)

	Metabolites	AD Mean±SD	CN Mean±SD	% Difference (%)	P*
Parietal GM	NAA	2.00±0.30	2.22±0.26	−10.0	0.044
	mI	1.39±0.19	1.26±0.18	10.3	0.048
	NAA/Cr	1.28±0.11	1.44±0.12	−11.1	0.0009
	mI/Cr	0.90±0.12	0.82±0.10	9.8	0.07
	NAA/mI	1.45±0.21	1.78±0.25	−18.5	0.0003
Frontal GM	NAA	2.01±0.25	2.05±0.28	−2.0	0.68
	mI	1.47±0.35	1.26±0.19	16.7	0.40
	NAA/Cr	1.27±0.11	1.39±0.12	−8.6	0.006
	mI/Cr	0.94±0.22	0.86±0.10	9.3	0.93
	NAA/mI	1.41±0.25	1.64±0.23	−14.0	0.32
Parietal WM	NAA	2.40±0.24	2.51±0.25	−4.4	0.31
	mI	1.58±0.27	1.46±0.18	8.2	0.26
	NAA/Cr	1.49±0.11	1.61±0.13	−7.4	0.02
	mI/Cr	0.98±0.13	0.94±0.11	4.3	0.16
	NAA/mI	1.54±0.20	1.73±0.22	−11.0	0.03
Frontal WM	NAA	2.44±0.31	2.45±0.30	−0.4	0.72
	mI	1.41±0.26	1.41±0.17	0.0	0.97
	NAA/Cr	1.48±0.11	1.54±0.14	−3.9	0.12
	mI/Cr	0.86±0.13	0.88±0.09	−2.3	0.47
	NAA/mI	1.77±0.31	1.75±0.21	1.1	0.93

^*P values are for multivariate analysis of covariance using an LME model.