TABLE 5.
Comparison of Literature Values of Classification Between AD and CN Using MRSI or SV MRS
|
Classification (%) |
|||||
|---|---|---|---|---|---|
| Authors | Overall Classification | Sensitivity | Specificity | Metabolites (Brain Lobe) | MRS Method |
| Fernandez et al, 200565 | 90 (n=20) | 90 | 90 | mI/NAA (Temporo-parietal) | SV M RSTE=35ms |
| Schuff et al, 200210 | 83 (n=110) | 84 | 83 | NAA (Medial temporal) | MRSI TE=135 ms |
| Dixon et al, 200266 | 68–70 (n=25) | NA | NA | NAA (Hippocampus) | SV MRS TE=90ms |
| Kantarci et al, 200267 | NA (n=83) | 82 | 80 | NAA/mI (Posterior cingulate) | SV MRS TE=30ms |
| Antuono et al, 200168 | 80 (n=30) | NA | NA | mI/Cr+NAA/Cr (Posterior cingulate) | SV MRS TE=68ms |
| Mackay et al, 199647 | 82 (n=20) | 100 | 73 | NAA/Cho (Posterior mesial) | PRESS MRSI TE=272 ms |
| Shonk et al, 199524 | NA (n=97) | 83 | 98 | NAA/mI (Occipital) | SV MRS TE=30ms |