Table 2.

Multivariate analysis of demographic and MRI variables

Predictor	Estimate	SE	p value	HR	95% CI
Age	0.003	0.04	0.94	1.00	0.92–1.10
Education	−0.02	0.12	0.87	0.98	0.78–1.24
Gender	0.67	0.61	0.27	1.96	0.59–6.52
cGM	−2.30	1.48	0.12	0.10	0.01–1.81
HC	−1.18	0.56	0.03	0.31	0.10–0.92
Lacunes	0.10	0.58	0.86	1.11	0.36–3.42
WMH	−0.31	0.38	0.41	0.73	0.35–1.54

HR = hazard ratio; cGM = cortical gray matter; HC = hippocampal volume; WMH = white matter hyperintensity volume.