Table 2. .
LOD for K100 at |
HLOD at |
|||||
Disease-Allele Frequency .001 |
Disease-Allele Frequency .001 |
|||||
Penetrances (%) |
Phenocopy Rate .001 | Phenocopy Rate .01 | Disease-Allele Frequency .01 and Phenocopy Rate .001 |
Phenocopy Rate .001 | Phenocopy Rate .01 | Disease-Allele Frequency .01 and Phenocopy Rate .001 |
65 | 3.2 | 3.2 | 3.2 | 3.6 | 3.5 | 3.3 |
75 | 3.4 | 3.4 | 3.4 | 3.7 | 3.7 | 3.5 |
85 | 3.5 | 3.5 | 3.5 | 3.9 | 3.8 | 3.6 |
95 | 3.3 | 3.3 | 3.3 | 3.7 | 3.7 | 3.4 |
Note.— Peak parametric HLODs are shown for all seven pedigrees combined (with 45% of families linked).