Figure 7.

LT-induced hypoxia. (a) Mice were injected i.p. with 1.0 ml of PBS or 100 μg LT. Serum EPO measurements at each time point represent averages of values assessed for two samples, with each sample representing sera pooled from three mice. The exception is the 72-hour time point for BALB/cJ, which represents measurement of one sample composed of pooled sera from three mice. (b) Liver extracts from BALB/cJ or C57BL/6J mice treated i.p. with 100 μg LT for 6, 24, 60, and 72 hours were analyzed for HSP70 levels by Western blot.