Table 2.
Comparison of opioid peptide sequences
| Peptide | Sequence |
|---|---|
| Proopiomelanocortin products | |
| β-Endorphin(1–27) | YGGFMTSEKSQTPLVL (10) |
| β-Endorphin(1–31) | YGGFMTSEKSQTPLVL (14) |
| Proenkephalin products | |
| Leu-enkephalin | YGGFL |
| Met-enkephalin | YGGFM |
| Met-enkephalin-Arg-Phe | YGGFMRF |
| Met-enkephalin-Arg-Gly-Leu | YGGFMRGL |
| Metorphamide | YGGFMRRV-NH2 |
| BAM 12 | YGGFMRRVGRPE |
| BAM 18 | YGGFMRRVGRPEWW (4) |
| BAM 22 | YGGFMRRVGRPEWW (7) |
| Peptide E | YGGFMRRVGRPEWW (10) |
| Prodynorphin products | |
| Dynorphin A1–7 | YGGFLRR |
| Dynorphin A1–8 | YGGFLRRI |
| Dynorphin A1–9 | YGGFLRRIR |
| Dynorphin A1–13 | YGGFLRRIRPKLK |
| Dynorphin A1–17 | YGGFLRRIRPKLKWDNQ |
| Dynorphin AB1–32 | YGGFLRRIRPKLKWD (17) |
| Dynorphin B1–13 | YGGFLRRQFKVVT |
| Leumorphin | YGGFLRRQFKVVTR (15) |
| α-Neo-endorphin | YGGFLRKYPK |
| β-Neo-endorphin | YGGFLRKYP |
Amino acid sequences of peptides derived from the opioid precursor proteins proopiomelanocortin, proenkephalin, and prodynorphin, using the single letter amino acid notation. Where only a partial sequence is given, the number of additional amino acids is indicated in parentheses.