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. 2000 Apr 11;97(8):4279–4284. doi: 10.1073/pnas.97.8.4279

Table 1.

Steroid studies: Blood values at M0, M6, and M12

Group n DHEAS, μmol/liter
Testo, nmol/liter
ADG, nmol/liter
E2, pmol/liter
M0 M6 M12 M0 M6 M12 M0 M6 M12 M0 M6 M12
Men <70
 DHEA 36 2.90  ± 0.19 10.4  ± 0.92**†† 7.22  ± 0.65**†† 18.4  ± 1.1 20.9  ± 1.11 18.1  ± 0.91 14.3  ± 1.03 29.0  ± 2.42** 23.4  ± 2.98** 71  ± 2.7 78  ± 3.2 81  ± 2.4*
 Placebo 31 2.65  ± 0.16 1.81  ± 0.19 2.66  ± 0.19 20.0  ± 1.15 18.7  ± 1.09 8.2  ± 0.96 15.2  ± 1.50 15.6  ± 1.67 16.2  ± 1.76 73  ± 3.8 73  ± 4.0 76  ± 3.7
Men >70
 DHEA 30 2.44  ± 0.22 10.3  ± 1.06**†† 8.98  ± 0.87**†† 19.3  ± 1.12 20.6  ± 0.96 20.7  ± 1.17 13.7  ± 1.28 33.5  ± 3.06** 35.3  ± 3.61** 74  ± 3.4 76  ± 3.4 81  ± 4.4*
 Placebo 36 2.14  ± 0.13 1.44  ± 0.16 2.00  ± 0.19 19.3  ± 1.48 20.1  ± 1.76 18.6  ± 1.81 14.0  ± 1.29 15.9  ± 1.88 15.1  ± 1.48 74  ± 3.0 79  ± 3.3 80  ± 3.4
Women  <70
 DHEA 35 2.01  ± 0.16 8.03  ± 0.71**†† 5.24  ± 0.43** 1.30  ± 0.1 2.3  ± 0.1* 1.60  ± 0.1 4.5  ± 0.5 29.5  ± 3.6**†† 20.5  ± 2.5**†† 28  ± 1.8 39  ± 1.6** 37  ± 1.6**
 Placebo 35 2.19  ± 0.19 1.54  ± 0.16 2.11  ± 0.24 1.16  ± 0.08 1.3  ± 0.09 1.23  ± 0.08 3.9  ± 0.43 3.90  ± 0.36 4.2  ± 0.42 27  ± 1.3 29  ± 1.6 27  ± 1.9
Women  >70
 DHEA 31 1.66  ± 0.11 9.77  ± 1.09**†† 7.19  ± 0.57**†† 1.09  ± 0.09 2.35  ± 0.15* 1.92  ± 0.13* 3.3  ± 0.3 27.8  ± 2.0**†† 26.4  ± 2.5**†† 25  ± 1.2 37  ± 1.8** 35  ± 2.0**
 Placebo 34 1.81  ± 0.19 1.19  ± 0.13 1.57  ± 0.19 1.17  ± 0.11 1.31  ± 0.14 1.25  ± 0.12 3.8  ± 0.42 3.90  ± 0.47 3.90  ± 0.39 26  ± 1.4 26  ± 1.04 27  ± 1.7

*, P < 0.05; **, P < 0.01 vs. M0 of the same group. †, P < 0.05; ††, P < 0.01 vs. placebo group of same age and gender.