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. 2000 Apr 4;97(8):4285–4290. doi: 10.1073/pnas.080068597

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Morphology and phenotype of the 20A cell line, xenotransplanted into a SCID mouse. (A) Hematoxylin-eosin stain showing large cell lymphoma with high mitotic rate. (B) Immunoperoxidase stain with antibody against human CD20 (B cell antigen) showing cell-membrane staining in all lymphoma cells. (C) Immunoperoxidase stain with an antibody against K_i-67 (cell proliferation-related antigen) showing nuclear staining in 50–80%. (D) In situ hybridization for EBV-encoded RNA1 (EBER1) showing nuclear positivity in all lymphoma cells.