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RAD-mediated inhibition of in vivo growth of a malignant PTLD-like B cells; prevention of tumor growth. Fragments of tumors derived from EBV+ B cell lines 15A, 20A, and A2D6 were implanted into recipient SCID mice. The treatment with 5 mg/kg/day of the drug was started 3 days before the tumor implantation. The numbers of mice per group are shown in parentheses; lines depicting results from some of the mice are superimposed.
