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. 2000 Mar 21;97(8):4309–4314. doi: 10.1073/pnas.070525997

Figure 5.

Figure 5

Wild-type B/Yamagata/1/73 influenza virus and derivative viruses containing alterations in the viral NS1 ORFs. Influenza B/Yamagata NS genes and mRNA transcripts are schematically represented as in Fig. 1. Viral NS gene segments are represented by light-gray boxes and viral NS1 ORFs by white boxes. A 13-nt deletion in the B/201 NS gene is indicated by a vertical bar. Seventeen amino acids resulting from a frameshift in the B/201 NS1 ORF are indicated by a hatched bar (8). Deletion of nucleotide number 310 in the B/234 NS gene segment results in a frameshift encoding one leucine and then a stop codon, represented by a vertical bar. The B/234 viral NS1 protein also contains a glu → val change at amino acid position 66 (not shown). B/Yamagata, B/201, and B/234 NS genes have been described previously, (6, 8) and are shown here together for comparison of the NS1 ORFs. Length of B/AWBY NS gene as predicted from the literature is indicated (6).