Table 3.

Concomitant Venous Thromboembolism (VTE) and Risk of Death According to Cancer Type

Cancer type	Hazard of death associated with VTE (vs no VTE)
	Model A: unadjusted		Model B: adjusted for age, sex, race		Model C: adjusted for factors in Model B + cancer characteristics and treatment		Model D: adjusted for factors in Model C + comorbidity		Model E: adjusted for factors in Model D + socioeconomic status
	Hazard ratio	95% CI	Hazard ratio	95% CI	Hazard ratio	95% CI	Hazard ratio	95% CI	Hazard ratio	95% CI
Prostate	2.24	1.78–2.81	1.81	1.44–2.27	1.44	1.14–1.81	1.20	0.95–1.51	1.21	0.96–1.52
Breast	2.30	1.76–3.01	1.95	1.48–2.55	1.11	0.84–1.45	1.01	0.77–1.32	1.01	0.77–1.33
Bladder	2.80	2.17–3.62	2.84	2.20–3.66	1.57	1.21–2.03	1.54	1.19–2.00	1.43	1.13–1.80
Uterus	3.06	2.32–4.04	3.47	2.63–4.59	2.08	1.57–2.75	1.98	1.48–2.64	1.96	1.47–2.62
Lung	1.30	1.18–1.44	1.32	1.20–1.45	1.20	1.09–11.1	1.15	1.04–1.27	1.16	1.05–1.27
Colorectal	1.33	1.18–1.49	1.32	1.17–1.48	1.24	1.10–1.39	1.19	1.06–1.33	1.19	1.06–1.34
Lymphoma	1.95	1.62–2.34	1.82	1.52–2.19	1.78	1.48–2.14	1.62	1.35–1.96	1.63	1.35–1.97
Pancreas	1.31	1.10–1.55	1.35	1.14–1.60	1.28	1.08–1.52	1.26	1.06–1.49	1.26	1.06–1.49
Kidney	1.49	1.19–1.88	1.61	1.28–2.02	1.49	1.18–1.88	1.41	1.12–1.78	1.43	1.13–1.80
Ovary	1.27	1.00–1.61	1.16	0.91–1.47	1.35	1.07–1.72	1.32	1.04–1.68	1.32	1.03–1.68

Each row represents a unique model, as patients with each type of cancer were analyzed separately. Hazard ratio represents the hazard of death for patients with a concomitant VTE compared to patients with the same cancer type, but without a concomitant VTE. Cancer characteristics include stage at diagnosis and histologic grade.

CI = confidence interval.