Table 3.

Adjusted Risk Change Difference and Number Needed to Treat

	Adjusted Risk Change Difference	95% Confidence Interval	NNT*
UKPDS 10-year risk
All patients	−2.1%	(−3.7%, −0.5%)	48
Upper tercile UKPDS	−4.1%	(−7.1%, −1.0%)	24
Lower tercile UKPDS	−1.0%	(−2.4%, 0.5%)	–

Results shown are the adjusted differences in the pre–post changes in 10-year risk of myocardial infarction, fatal myocardial infarction, and sudden death between the intervention and control groups. Models adjust for age, comorbidity, severity of diabetes, and site of care between intervention and control groups.

*Estimated number needed to treat to reduce the risk of one cardiovascular disease event is derived from the 10-year adjusted risk change difference.