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. 2007 Jan 20;113(4):389–402. doi: 10.1007/s00401-006-0191-4

Table 2.

n−40 and Aβn−42 concentration (pmol/g) in temporal cortex

Control case # n−40 n−42
p3 p4 p3 p4
247 2 2 1 0.3
256 2 1 2 1
1,169 0.3 0.3 0.2a 0.2a

Brain samples were homogenized in formic acid as described in Materials and methods. Aliquots of the extracts were neutralized and subjected to PAGE and immunobloting. p4 bands migrated above the 3 kDa standards and bound mAb 6E10. p3 bands migrated near the 3 kDa standard and bound R162 or R226 but did not bind mAb 6E10

aThere was only one band in this extract. Its level was too low to be revealed by mAb 6E10 and so could not be identified as p3 or p4