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. 2002 Jul;9(4):156–166. doi: 10.1101/lm.48502

Figure 1.

Figure 1

PD098059 infusion into the entorhinal cortex (EC) prevents extracellular signal-regulated kinase (Erk) activation. (A) Representative photomicrographs showing decreased phospho-Erk immunoreactivity in the entorhinal area after 0.2 μg PD098059 infusion into one side compared with the vehicle-infused contralateral side (10-min time point). (B) In adjacent slices, 0.2 μg PD098059 does not decrease CREB immunoreactivity. (C) In the dorsal hippocampus in the same animal, 0.2 μg PD098059 infused into the EC does not decrease phospho-Erk.