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. 2003 Sep;47(9):2981–2983. doi: 10.1128/AAC.47.9.2981-2983.2003

TABLE 2.

Silent mutations and amino acid substitutions found in TEM-91 compared with TEM-1A and TEM-1B

β-Lactamase Codon (amino acid substitution, position) containing a mutation at positiona:
209 226 436 604 692 747 917
TEM-91 ATG (M, 3) TTC (F, 8) GGT (G, 78) GCG (A, 134) TGT (C, 164) ACG (T, 182) AAG (K, 240)
TEM-1A ATG (M, 3) TTC (F, 8) GGC (G, 78) GCG (A, 134) CGT (R, 164) ATG (M, 182) GAG (E, 240)
TEM-1B ATG (M, 3) TTT (F, 8) GGT (G, 78) GCT (A, 134) CGT (R, 164) ATG (M, 182) GAG (E, 240)
a

Standard numbering schemes for class A β-lactamases by Ambler et al. (1) and Leflon-Guibout et al. (16). Boldface nucleic acids are the mutation.