TABLE 2.
β-Lactam susceptibilities of K. pneumoniae FFUL 22K, E. coli DH5α(p 22K9), and E. coli TOP10(pMFA-2)
| β-Lactam | MIC (μg/ml)
|
||||
|---|---|---|---|---|---|
| K. pneumoniae FFUL 22K | E. coli DH5α(p22K9)a | E. coli DH5αb | E. coli TOP10(pMFA-2)c | E. coli TOP10(pBK-CMV)d | |
| Amoxicillin | >256 | >256 | 4 | >256 | 2 |
| Amoxicillin/clavulanic acid | 12 | 12 | 4 | 16 | 2 |
| Cefuroxime | 256 | >256 | 3 | >256 | 4 |
| Cefotaxime | 6 | 2 | 0.064 | 8 | 0.125 |
| Cefotaxime/clavulanic acid | >1 | 0.19 | NDe | >1 | ND |
| Ceftazidime | 256 | 96 | 0.25 | >256 | 0.75 |
| Ceftazidime/clavulanic acid | >4 | 1 | ND | >4 | ND |
| Aztreonam | 3 | 0.75 | 0.125 | 1.5 | 0.094 |
| Cefepime | 2 | 0.5 | 0.047 | ND | 0.047 |
| Imipenem | 0.25 | 0.19 | 0.19 | 0.38 | 0.25 |
a
E. coli DH5α (p22K9) expressed β-lactamase GES-1.
b
The susceptibility of E. coli DH5α is shown for comparison.
c
E. coli TOP10 (pMFA-2) expressed β-lactamase GES-1.
d
The susceptibility of E. coli TOP10 carrying the empty vector is also shown for comparison.
e
ND, not determined.