TABLE 1.
Organism | Strain | MIC (μg/ml)
|
||||
---|---|---|---|---|---|---|
HMR 1043
|
Daptomycin
|
Teicoplanin in MH | ||||
MH | CSMH | MH | CSMH | |||
Staphylococcus aureus | ||||||
Methicillin susceptible ATCC 25923 | 1 | 1 | 0.5 | 0.5 | 0.25 | 1 |
Methicillin susceptible | 2 | 0.5 | 0.5 | 0.25 | 0.125 | 1 |
Methicillin susceptible | 2M* | 2 | 1 | 0.25 | 0.125 | 1 |
Methicillin resistant | 3 | 1 | 0.5 | 0.25 | 0.25 | 1 |
Teicoplanin intermediate | 4 | 1 | 1 | 0.5 | 0.25 | 16 |
Teicoplanin intermediate | 4M | 4 | 2 | 1 | 0.25 | 16 |
VISA | 5 | 4 | 2 | 1 | 0.25 | 16 |
Staphylococcus epidermidis | ||||||
Methicillin susceptible ATCC 12228 | 6 | 0.5 | 0.5 | 0.25 | 0.125 | 1 |
Methicillin susceptible | 6M | 4 | 1 | 0.25 | 0.125 | 2 |
Methicillin susceptible | 7 | 1 | 0.5 | 0.25 | 0.125 | 1 |
Methicillin susceptible | 7M | 4 | 2 | 2 | 0.5 | 1 |
Methicillin resistant | 8 | 1 | 0.5 | 0.25 | 0.125 | 2 |
Methicillin resistant | 8M | 4 | 2 | 1 | 0.25 | 2 |
Teicoplanin resistant | 9 | 1 | 1 | 0.25 | 0.125 | 8 |
Teicoplanin resistant | 9M | 8 | 4 | 2 | 0.5 | 8 |
Staphylococcus haemolyticus | ||||||
Teicoplanin susceptible | 10 | 0.5 | 0.5 | 0.125 | 0.125 | 4 |
Teicoplanin resistant | 11 | 0.5 | 0.5 | 0.25 | 0.125 | 16 |
Teicoplanin resistant | 11M | 8 | 4 | 0.5 | 0.25 | 16 |
Enterococcus faecalis ATCC 29212 | 12 | 4 | 2 | 1 | 0.125 | 0.25 |
VanA 13 | 1 | 0.5 | 2 | 0.25 | 16 | |
VanB 14 | 4 | 2 | 1 | 0.25 | 0.25 | |
Enterococcus faecium ATCC 35667 | 15 | 2 | 1 | 2 | 0.25 | 0.5 |
VanA 16 | 2 | 1 | 2 | 0.5 | >16 | |
VanB 17 | 4 | 1 | 0.5 | 0.125 | 0.5 | |
Listeria monocytogenes ATCC 19115 | 18 | 8 | 4 | 4 | 0.5 | 0.5 |
18M | >16 | 4 | 4 | 0.5 | 0.5 | |
19 | 8 | 2 | 2 | 0.25 | 0.5 | |
Streptococcus pneumoniae | ||||||
Penicillin susceptible ATCC 49619 | 20 | 0.125 | 0.125 | 0.125 | 0.03 | 0.125 |
Penicillin susceptible | 20M | 1 | 1 | 0.125 | 0.06 | 0.125 |
Penicillin susceptible | 21 | 1 | 0.5 | 0.125 | 0.03 | 0.125 |
Penicillin susceptible | 21M | 4 | 0.5 | ND | ND | ND |
Penicillin resistant | 22 | 0.5 | 0.25 | 0.125 | 0.03 | 0.125 |
Streptococcus pyogenes ATCC 19615 | 23 | 1 | 0.5 | 1 | 0.125 | 0.125 |
24 | 1 | 0.5 | 0.06 | 0.03 | 0.125 | |
Streptococcus agalactiae ATCC 13813 | 25 | 1 | 1 | 0.25 | 0.06 | 0.25 |
26 | 1 | 0.5 | 0.25 | 0.06 | 0.125 |
M*, mutant strain with decreased susceptibility; VISA, vancomycin-intermediate Staphylococcus aureus; ND, not determined.