TABLE 2.
LC90s of peptides
| Peptide | Meana LC90 (μg/ml) ± SD against:
|
||||
|---|---|---|---|---|---|
| E. coli | S. aureus | C. albicans | P. aeruginosa | E. faecium | |
| hBD3 | 6 ± 1.4 | 10 ± 4.5 | 17 ± 3.2 | ||
| hBD3A | 5 ± 0.8 | 14 ± 8.9 | 15 ± 5.1 | ||
| hBD3Δ8 | 6 ± 0.4 | 16 ± 5.4 | NDb | ||
| hBD3Δ10 | 6 ± 1.9 | 17 ± 10.2 | ND | ||
| ABU-hBD3 | 1 ± 0.2 | 5 ± 0.7 | 17 ± 3.1 | 4 ± 1.8 | 2 ± 0.5 |
| STRC06 | 20 ± 4.6 | >20 | >20 | ||
| CHRG01 | 1 ± 0.1 | >20 | >20 | 4 ± 0.4 | >20 |
| CHRG02 | 4 ± 0.3 | >20 | >20 | ||
| CHRG04 | 10 ± 2.8 | >20 | >20 | ||
| CHRG06 | 9 ± 1.8 | >20 | >20 | ||
| CHRG07 | 19 ± 3.4 | 17 ± 3.4 | 15 ± 2.1 | 2 ± 0.7 | 3 ± 1.6 |
a
Based on three independent assays.
b
ND, not done.