TABLE 5.

Results of a stratified Cox proportional hazard model describing independent relations between both empirical and definitive antimicrobial therapy and risk of death during late follow-up^a

Characteristic	Hazard ratio	95% CI	P value
Empirical antimicrobial therapy
Adequate combination therapy	1.0
Adequate monotherapy	3.7	1.0-14.1	0.05
Inadequate therapy	5.0	1.2-20.4	0.02
Definitive antimicrobial therapy
Adequate combination therapy	1.0
Adequate monotherapy	0.70	0.30-1.7	0.42
Inadequate therapy	2.6	1.1-6.7	0.04
Hospitalization on the surgical intensive care unit
No	1.0
Yes	3.2	1.2-8.9	0.02
Bacteremia of urinary or vascular origin
No	1.0
Yes	0.21	0.05-0.94	0.04

^aThe model was stratified on dummy variables coding for severe sepsis and shock to account for violations of the proportional hazard assumption. Late follow-up started on the day of receipt of the antibiogram and extended to the end of day 30 post bacteremia.