Figure 4.
Confocal scanner image of Cy3-labeled C. burnetti binding to immobilized AMPs (right). Control antibody for C. burnetti is shown abbreviated as anti-Cox. PBS served as a negative (−) control and anti-chicken IgY as a positive (+) control. Incorporation of anti-chicken IgY allowed comparison of slides between independent experiments. A. Concentration-dependence curves for Cy3-labeled C. burnetti binding to polymyxin B (○) and bactenecin (●). B. Concentration-dependence curves for Cy3-C. burneti binding to cecropin A (●), cecropin B (▼) and cecropin P (■). Error bars indicate standard deviation (n = 4 slides). Fluorescent intensities were normalized with respect to chicken positive control.