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. Author manuscript; available in PMC: 2007 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2006 Sep 8;41(11):1694–1703. doi: 10.1016/j.freeradbiomed.2006.09.002

Figure 4A.

Figure 4A

Shows a significant decrement in GSH levels in brain mitochondria isolated from saline-injected gerbils and subsequently treated with AAPH, Fe2+/H2O2 or Aβ (1-42) compared to GSH levels in brain mitochondria isolated from saline-injected gerbils not subjected to treatment of any oxidant. Also shown is the protection of GSH levels in brain mitochondria isolated from gerbils previously injected i.p. with D609 1 h before sacrifice and treated with AAPH, Fe2+/H2O2 or Aβ (1-42) compared to GSH levels in brain mitochondria isolated from saline-treated gerbils and then treated with oxidants. *p<0.01 and **p<0.001 compared to control, # p<0.01 and ## p<0.01 compared to oxidant treatment. The data are presented as mean ± SEM expressed as percentage of control (n=6).