Skip to main content
. Author manuscript; available in PMC: 2007 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2006 Sep 8;41(11):1694–1703. doi: 10.1016/j.freeradbiomed.2006.09.002

Figure 5.

Figure 5

Shows the increased level of cytochrome-c released from brain mitochondria isolated from saline-injected gerbils and treated with various oxidants (AAPH, Fe2+/H2O2 or Aβ (1-42) as compared to cytochrome-c released from brain mitochondria isolated from saline-injected gerbils but not subjected to treatment of any oxidant. Also shown is the decrement of cytochrome-c release from brain mitochondria isolated from gerbils previously injected i.p. with D609 1 h before sacrifice and treated with AAPH, Fe2+/H2O2 or Aβ (1-42) compared to that released from brain mitochindria isolated from gerbils subjected to oxidant treatment. The D609 only treatment shows significantly less cytochrome-c release compared control. *p<0.01 as compared to control, # p<0.01 compared to oxidant treatment. The data are presented as mean ± SEM expressed as percentage of control (n=5).