Table 2.
Independent Effect of Clinical Abnormalities on Complications
| All Complications, 95% CI§ | Cardiopulmonary Complications, 95% CI∥ | |
|---|---|---|
| Adjusted effect of most severe abnormality measure | ||
| Adjusted odds for no abnormalities before surgery | Referent | Referent |
| Adjusted odds for minor abnormalities before surgery | 0.70 (0.28 to 1.73) | 0.80 (0.27 to 2.33) |
| Adjusted odds for major abnormalities before surgery | 2.82† (1.38 to 5.79) | 2.61‡ (1.11 to 6.12) |
| Model c-statistic | 0.7079 | 0.7326 |
| Adjusted effect of additional abnormalities: | ||
| Adjusted odds for no major abnormalities before surgery | Referent | Referent |
| Adjusted odds for 1 major abnormality and no minor abnormalities before surgery | 2.50‡ (1.04 to 6.00) | 1.91 (0.65 to 5.60) |
| Adjusted odds for 1 major abnormality plus minor abnormalities before surgery | 2.50 (0.75 to 8.32) | 2.50 (0.63 to 9.91) |
| Adjusted odds for >1 major abnormality before surgery | 9.66* (2.83 to 32.99) | 8.14† (2.11 to 31.34) |
| Model c-statistic | 0.7156 | 0.7314 |
| Adjusted effect of changes in abnormalities between admission and time of surgery | ||
| Adjusted odds for no abnormalities on admission and prior to surgery | Referent | Referent |
| Adjusted odds for minor abnormalities on admission and/or prior to surgery but nomajor abnormalities | 0.86 (0.38 to 1.92) | 0.89 (0.33 to 2.41) |
| Adjusted odds for no or minor abnormalities on admission but major abnormalities prior to surgery | 3.28 (0.55 to 19.54) | 6.09 (0.97 to 38.17) |
| Adjusted odds for major abnormalities on admission but none or minor abnormalities only prior to surgery | 0.82 (0.24 to 2.74) | 0.87 (0.21 to 3.60) |
| Adjusted odds for major abnormalities on admission and major abnormalities prior to surgery | 2.79‡ (1.22 to 6.37) | 2.32 (0.85 to 6.34) |
| Model c-statistic | 0.7185 | 0.7124 |
*
P≤.001
†
P≤.01
‡
P≤.05
§
Model adjusted for COPD, CHF, delirium, and dependent in transfers. Locomotion and RAND not retained in model by stepwise procedure
∥
Model adjusted for COPD, delirium, and locomotion. RAND, dependent in transfers, and CHF not retained in model by stepwise procedure
CI, confidence interval; FIM, functional independence measure; APACHE, Acute Physiology And Chronic Health Evaluation