TABLE 1.
Macrophage Phagocytic Capacity
Particle | Wild-type | vamp3 null |
---|---|---|
Zymo. | 37 ±7 | 48 ± 9 |
IgG-Zymo. | 47 ±8 | 56 ± 10 |
COZ | 64 ± 7 | 52 ± 8 |
Latex | > 100 | > 100 |
wt and vamp3 null BMM were incubated with ~65 zymosan or opsonized zymosan particles or ~125 latex beads per cell for 1 h at 37°C. Data shown indicate the number of ingested particles per BMM (average ± SD) from three independent experiments.