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. Author manuscript; available in PMC: 2007 Mar 17.
Published in final edited form as: J Mol Biol. 2006 Dec 2;366(3):703–710. doi: 10.1016/j.jmb.2006.11.077

Figure 2.

Figure 2

Comparison of apo- and RNA-bound U2AF65-RRM1. U2AF65-RRM1 in the presence (green) or absence (blue) of RNA ligand. When alternative conformations are present, major conformations of the apo-RRM1 side chains are colored yellow, minor conformations are colored orange. (a) Superimposed ribbon diagrams. (b) View of the α1/β2 loop. (c) Comparison of aromatic residues (Phe197, Phe199, Tyr152) in the RNP motifs. Sigma-A weighted, |Fo|-|Fc| omit electron density for side chain atoms was calculated using Shelxpro28 and is shown at 5σ contour level. (d) View of Arg150. (e) View of Lys225 and Arg227.