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. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Int J Parasitol. 2006 Nov 27;37(3-4):307–316. doi: 10.1016/j.ijpara.2006.10.014

Fig. 1.

Fig. 1

The CpPKS1 loading unit consists of acyl ligase (AL) and acyl carrier protein (ACP) domains. The AL domain contains two highly conserved motifs responsible for the adenylation and ATPase activities. The ACP domain contains the phosphopantetheinyl binding domain (Ppant) for the attachment of a phosphopantetheinyl moiety to the conserved serine reside. Position-specific scoring matrix (PSSM) logos for the three domains were generated from the specified numbers of sequences retrieved from the GenBank™ protein database. Within each logo, the letter(s) represent the respective amino acid position in each motif, whereas the size of each letter represents the relative abundance of the respective amino acid within the sequences used for comparison. Motifs for the three conserved domains in the CpPKS1 loading unit are provided in parentheses for comparison with the PSSM logos. Load = loading unit, Mod = elongation modules, Red = reductase domain.