Table 2.
Mean (±SEM) VMH regional volumes and soma areas of right and left hemispheres of adult TFM male rats and WT male and female littermate controls in each subdivision of the VMH. VMHdm right volume was significantly greater than VMHdm left volume only in TFM males. VMHvl left volume was marginally greater than VMHvl right volume in TFM males and WT males.
|
Females (n = 10) |
Tfms (n = 8) |
Males (n = 6) |
||||
|---|---|---|---|---|---|---|
| Left | Right | Left | Right | Left | Right | |
| VOLUME (mm^3 ×10^−3) | ||||||
| Anterior | 34.8+/− 3.5 | 36.1+/−3.7 | 35.9+/−3.7 | 42.1+/−4.8 | 31.6+/−5.0 | 32.8+/−3.9 |
| Ventrolateral | 166.6+/−4.8 | 165.9+/−4.6 | 180.8+/−3.6(†) | 166.4+/−4.3 | 206.7+/−9.0 (†) | 190.2+/−7.1 |
| Central | 142.6+/−6.0 | 142.9+/−5.3 | 146.7+/−10.0 | 144.0+/−7.8 | 153.1+/−4.8 | 153.9+/−9.5 |
| Dorsomedial | 162.1+/−5.2 | 164.3+/−5.4 | 165.6+/−5.6 (*) | 174.4+/−4.4 | 178.2+/−9.1 | 185.1+/−10.1 |
| SOMA (um^2) | ||||||
| Anterior | 172.7+/−4.1 | 180.6+/−2.8 | 179.1+/−2.3 | 172.8+/−3.2 | 184.6+/−3.9 | 185.2+/−3.7 |
| Ventrolateral | 190.9+/−2.1 | 192.0+/−2.3 | 195.3+/−4.18 | 192.9+/−5.2 | 207.3+/−4.2 | 203.6+/−3.4 |
| Central | 173.2+/−2.9 | 172.9+/−2.4 | 172.8+/−2.0 | 175.3+/−1.8 | 180.4+/−3.2 | 184.7+/−3.0 |
| Dorsomedial | 187.0+/−2.8 | 191.8+/−2.4 | 194.3+/−4.8(†) | 193.8+/−4.7 | 207.5+/−3.5 | 209.0+/−3.1 |
†
Marginally larger than right hemisphere (P=0.05 for Tfms and P=0.06 for Males)
*
Significantly smaller than right hemisphere (P < 0.02)