FIG. 9.
Colonization of Y. pseudotuberculosis yopH double mutants. Mice were intranasally inoculated with ∼8 × 102 CFU of wild-type Y. pseudotuberculosis or mutants of the yopHE, yopHO, yopHM, yopHJ, or yopEOMJ strains. Four days postinoculation lungs were weighed, homogenized, and plated for CFU. Black circles represent the CFU recovered from individual mice, open circles indicate that the number of CFU was below the limit of detection, and bars represent the geometric mean. P values were determined by a two-tailed Student's t test. *, P < 0.05.