TABLE 1.

Differentially expressed genes in the sigM-overexpressing strain relative to wild-type^a

Gene productb	Locus	Change in expression (fold)	SD (fold)	P value
FadD34	Rv0035	−2.2	0.015	8.44E-05
Conserved hypothetical proteins*	Rv0313	−2.2	0.042	3.11E-04
CMP*	Rv0479c	−2.0	0.069	2.54E-03
Tuf	Rv0685	−2.0	0.057	1.25E-03
CMP*	Rv3092c	2.1	0.040	1.83E-02
Hypothetical oxidoreductase	Rv3093c	4.1	0.063	2.94E-02
Conserved hypothetical proteins*	Rv3094c	2.7	0.036	2.72E-02
Hypothetical transcriptional regulatory protein*	Rv3095	1.9	0.039	3.24E-02
Conserved hypothetical proteins* (alanine and proline rich)	Rv3439c	2.2	0.042	3.98E-02
HP*	Rv3440c	3.2	0.042	3.89E-03
EsxT	Rv3444c	13.0	0.035	4.60E-04
EsxU	Rv3445c	3.2	0.082	4.61E-02
CMP*	Rv3447c	8.4	0.022	2.50E-02
MycP4	Rv3449	5.4	0.025	6.67E-03
EsxE	Rv3904c	2.2	0.014	9.36E-03
EsxF	Rv3905c	2.4	0.003	2.70E-02
Conserved hypothetical proteins*	Rv3906c	6.3	0.044	1.30E-02
SigM	Rv3911	19.7	0.057	4.20E-04

^aShown is a summary of genes over-/underexpressed >1.9-fold in the SigM conditionally overexpressing strain of M. tuberculosis. Results shown are relative to wild-type strain containing the empty vector, pSCW38. SD, standard deviation.

^bThe asterisks denote gene products annotated as either conserved hypothetical proteins, conserved membrane proteins (CMP), or hypothetical proteins (HP).