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Ability for LPS to protect against challenge with F. tularensis or F. novicida
| Immunization | Survival (no. of mice surviving/no. of mice in group) after challenge with:a
|
|
|---|---|---|
| F. tularensis subsp. holarctica | F. novicida | |
| F. tularensis subsp. tularensis LPS | 6/6 | 0/6 |
| F. novicida LPS | 0/6 | 4/6 |
| Naïve | 0/6 | 0/6 |
Survival of mice following immunization with F. tularensis subsp. tularensis or F. novicida LPS and subsequent challenge 21 days postimmunization. No cross-protection was afforded.
